Surely you can save online. But you cannot save online at preview mode for preview mode uses a temporary db and the changes are only applied to the temporary db file.
Code:
var rs = new ActiveXObject("ADODB.Recordset");
rs.open("select * from mytable", conn, 1, 2);
rs.addNew();
rs.fields(0).value = "xxxxxxx";
rs.fields(1).value = "xxxxxxxxxx";
...
rs.update();